Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31469758 | 1.00 | GABRA1 (0.46) | GABRA1GABRG2GABRB3GABRA5ALDH1A1 | |
| SCHEMBL31469810 | 0.87 | ALDH1A1 (0.52) | ALDH1A1GSK3BOXER1MEN1KMT2A | |
| SCHEMBL31469733 | 0.79 | GABRA1 (0.54) | GABRA1GABRG2GABRB3GABRA5ALDH1A1 | |
| SCHEMBL25111402 | 0.76 | KDM4E (0.47) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL30099640 | 0.76 | KDM4E (0.47) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL6086148 | 0.71 | ALDH1A1 (0.52) | ALDH1A1HIF1AMEN1KMT2AKDM4E | |
| SCHEMBL5240374 | 0.69 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDCYP2C19CYP2C9 | |
| SCHEMBL5235211 | 0.69 | ALDH1A1 (0.43) | GABRA1GABRG2GABRB3GABRA5ALDH1A1 | |
| SCHEMBL14916391 | 0.69 | FABP4 (0.43) | GABRA1GABRG2GABRB3GABRA5ALDH1A1 | |
| SCHEMBL21848316 | 0.69 | TAS2R14 (0.38) | ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025030002-A2 | DGK TARGETING COMPOUNDS AND USES THEREOF | ARVINAS OPERATIONS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |