Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25340274 | 0.85 | GRM1 (0.52) | GRM1CHRM4MAP4K4SMOCHRM2 | |
| SCHEMBL25340276 | 0.85 | GRM1 (0.52) | GRM1CHRM4MAP4K4SMOCHRM2 | |
| SCHEMBL4573088 | 0.85 | CHRM4 (0.58) | GRM1CHRM4ALOX5MAP4K4 | |
| SCHEMBL31383652 | 0.83 | MAP4K4 (0.58) | GRM1CHRM4MAP4K4 | |
| SCHEMBL31383595 | 0.83 | MAP4K4 (0.58) | GRM1CHRM4MAP4K4 | |
| SCHEMBL14837556 | 0.81 | PIK3CD (0.40) | GRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12100509 | 0.78 | GRM1 (0.70) | GRM1CHRM4SMO | |
| SCHEMBL19994345 | 0.78 | ALOX5 (0.44) | GRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19994434 | 0.78 | ALOX5 (0.44) | GRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4573077 | 0.78 | CTSB (0.44) | GRM1CHRM4MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025029897-A1 | SUBSTITUTED PYRAZOLOPYRIDINES | NEURO3 THERAPEUTICS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |