Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573301 | 0.85 | MAP4K4 (0.58) | CTSBCTSSCTSKMAP4K4OGA | |
| SCHEMBL8117492 | 0.85 | MAP4K4 (0.58) | CTSBCTSSCTSKMAP4K4OGA | |
| SCHEMBL4573074 | 0.84 | CTSB (0.45) | CTSBCTSSCTSKMAP4K4GRM1 | |
| SCHEMBL4574023 | 0.82 | PIK3CD (0.43) | CTSBCTSSCTSKMAP4K4GRM1 | |
| SCHEMBL4573090 | 0.80 | CHRM4 (0.45) | GRM1CHRM4 | |
| SCHEMBL4574031 | 0.80 | OGA (0.47) | MAP4K4OGAUCHL3ROCK2PTGDR | |
| SCHEMBL4573088 | 0.78 | CHRM4 (0.58) | MAP4K4GRM1CHRM4ROCK2 | |
| SCHEMBL31469902 | 0.78 | GRM1 (0.51) | MAP4K4GRM1CHRM4 | |
| SCHEMBL4573182 | 0.76 | PIK3CD (0.41) | CTSBCTSSCTSKMAP4K4GRM1 | |
| SCHEMBL4573147 | 0.75 | GRM1 (0.39) | CTSBCTSSCTSKGRM1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |