SCHEMBL31470604

SCHEMBL31470604

NNc1ccc(S)c(N)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
IDO1 P14902 1/20 0.35
CYP2C19 P33261 1/20 0.35
PTGS2 P35354 1/20 0.35
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12287691 0.77 TDP1 (0.46) TDP1LMNACYP1A2CYP3A4CYP2D6
SCHEMBL7048225 0.74 TDP1 (0.33) TDP1LMNACYP1A2CYP3A4CYP2D6
SCHEMBL20311540 0.73 TDP1 (0.36) TDP1LMNACYP1A2CYP3A4CYP2D6
SCHEMBL27870146 0.71 ALDH1A1 (0.48) TDP1LMNACYP3A4IDO1KDM4E
SCHEMBL2339940 0.71 TDP1 (0.55) TDP1CYP1A2CYP3A4CYP2C19KDM4E
SCHEMBL63124 0.69
SCHEMBL29464081 0.69
SCHEMBL3848790 0.69 TDP1 (0.55) TDP1LMNACYP3A4KDM4EPOLB
SCHEMBL64846 0.69
Hydrochloric Acid SCHEMBL10452826 0.67 PTK2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119569664-B Thiophenol compound and preparation method and application thereof 山东师范大学 2025-04-29 CN disclosed
CN-119569664-A Thiophenol compound and preparation method and application thereof 山东师范大学 2025-03-07 CN disclosed