SCHEMBL31470976

SCHEMBL31470976

O=C1OCc2ccccc2-c2cc(F)ccc21

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.61
MAOA P21397 5/20 0.61
MAPK14 Q16539 2/20 0.49
NR3C2 P08235 3/20 0.47
ALDH1A1 P00352 3/20 0.45
MAPT P10636 3/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
KDM4E B2RXH2 1/20 0.45
TYMS P04818 1/20 0.45
CYP1A2 P05177 1/20 0.45
HPGD P15428 1/20 0.45
CYP2C19 P33261 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PPIA P62937 1/20 0.44
RAB9A P51151 1/20 0.42
AR P10275 1/20 0.41
RECQL P46063 1/20 0.41
PRF1 P14222 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25386767 1.00 MAOB (0.61) MAOBMAOAMAPK14NR3C2ALDH1A1
SCHEMBL25386333 0.90 MAOB (0.54) MAOBMAOAMAPK14ALDH1A1MAPT
SCHEMBL856120 0.84 MAOB (0.62) MAOBMAOAALDH1A1MAPTLMNA
SCHEMBL30132801 0.84 MAOB (0.62) MAOBMAOAALDH1A1MAPTLMNA
SCHEMBL25387025 0.82 MAPK14 (0.42) MAOBMAOAMAPK14NR3C2ALDH1A1
SCHEMBL31470974 0.82 MAPK14 (0.42) MAOBMAOAMAPK14NR3C2ALDH1A1
SCHEMBL31503957 0.82 MAOA (0.83) MAOBMAOAALDH1A1MAPTLMNA
SCHEMBL2208963 0.82 MAOA (0.83) MAOBMAOAALDH1A1MAPTLMNA
SCHEMBL31621082 0.80 MAPT (0.61) MAOBMAOAALDH1A1MAPTLMNA
SCHEMBL365201 0.80 MAPT (0.61) MAOBMAOAALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250154323-A1 THIONOLACTONES AS ADDITIVES FOR VINYL NETWORK DEGRADATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-05-15 US disclosed