Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.83 |
| ▸ | MAOB | P27338 | 5/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | TYMS | P04818 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31503957 | 1.00 | MAOA (0.83) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL11522370 | 0.91 | MAOA (1.00) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL29448271 | 0.91 | MAOA (1.00) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL6353583 | 0.91 | MAOA (1.00) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL6903786 | 0.91 | MAOA (1.00) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL22284 | 0.91 | MAOA (1.00) | MAOAMAOBALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL11215152 | 0.88 | MAOA (0.95) | MAOAMAOBALDH1A1KDM4EHPGD | |
| Water SCHEMBL11007472 | 0.88 | MAOA (0.95) | MAOAMAOBALDH1A1KDM4EHPGD | |
| Fluoride SCHEMBL8592140 | 0.88 | MAOA (0.95) | MAOAMAOBALDH1A1KDM4EHPGD | |
| Benzene SCHEMBL18492989 | 0.88 | MAOA (0.95) | MAOAMAOBALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250352452-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2025-11-20 | — | — | US | disclosed |
| EP-4626385-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-10-08 | — | — | EP | disclosed |
| US-12377037-B2 | Cleavable comonomer strategy for accelerating removal of gel nail polish | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-08-05 | — | — | US | disclosed |
| US-20250154323-A1 | THIONOLACTONES AS ADDITIVES FOR VINYL NETWORK DEGRADATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-05-15 | — | — | US | disclosed |
| US-20240423894-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2024-12-26 | — | — | US | disclosed |
| CN-118909180-A | Main/side chain degradable acrylic ester polymer containing sulfur ester and dynamic boric acid ester structure and preparation method thereof | 华南理工大学 | 2024-11-08 | — | — | CN | disclosed |
| WO-2024119140-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-06-06 | — | — | WO | disclosed |
| WO-2024119140-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-06-06 | — | — | WO | disclosed |
| WO-2023154756-A2 | THIONOLACTONES AS ADDITIVES FOR VINYL NETWORK DEGRADATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-08-17 | — | — | WO | disclosed |
| US-7982045-B2 | 2′-substituted 1,1′-biphenyl-2-carboxamides, processes for their preparation, their use as medicaments, and pharmaceutical preparations comprising them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-07-19 | — | — | US | disclosed |
| US-20090087571-A1 | LOW SHRINKAGE EPOXY-CATIONIC CURABLE COMPOSITION | HENKEL AG & CO., KGAA (DE) | 2009-04-02 | — | — | US | disclosed |
| WO-2007135094-A1 | LOW SHRINKAGE EPOXY-CATIONIC CURABLE COMPOSITIONS | HENKEL AG & CO. KGAA (DE) | 2007-11-29 | — | — | WO | disclosed |
| EP-1222163-B1 | 2'-SUBSTITUTED 1,1'-BIPHENYL-2-CARBONAMIDES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-07-12 | — | — | EP | disclosed |
| US-20040102513-A1 | 2'-Substituted 1,1'-biphenyl-2-carboxamides, processes for their preparation, their use as medicaments, and pharmaceutical preparations comprising them | AVENTIS PHARMA DEUTSCHLAND GMBH | 2004-05-27 | — | — | US | disclosed |
| US-6686395-B2 | THERAPY OF A CARDIAC ARRYTHMIA WHICH CAN BE ELIMINATED BY ACTION POTENTIAL PROLONGATION; POTASSIUM CHANNEL MODULATOR | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-02-03 | — | — | US | disclosed |
| US-20030171351-A1 | 2'-substituted 1,1'-biphenyl-2-carboxamides, process for their preparation, their use as medicaments, and pharmaceutical preparations comprising them | AVENTIS PHARMA DEUTSCHLAND GMBH | 2003-09-11 | — | — | US | disclosed |
| US-6531495-B1 | Potassium channel | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-03-11 | — | — | US | disclosed |
| EP-1222163-A1 | 2'-SUBSTITUTED 1,1'-BIPHENYL-2-CARBONAMIDES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | Aventis Pharma Deutschland GmbH (DE) | 2002-07-17 | — | — | EP | disclosed |
| US-6350916-B1 | BASIC OXIDATION OF ALCOHOL USING PHOSPHINE, AMINE, ETHER OR CARBENE BASES | SYMYX TECHNOLOGIES, INC. | 2002-02-26 | — | — | US | disclosed |
| WO-2001025189-A1 | 2'-SUBSTITUTED 1,1'-BIPHENYL-2-CARBONAMIDES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12377037-B2 | Cleavable comonomer strategy for accelerating removal of gel nail polish | PRKDC, POLR1C, PIK3C3 | MAOA 352/4885MAOB 620/4885ALDH1A1 2906/4885 |
| US-20030171351-A1 | 2'-substituted 1,1'-biphenyl-2-carboxamides, process for their preparation, their use as medicaments, and pharmaceutical preparations comprising them | MLLT3, RYR2, KCNH1 | MAOA 953/4885MAOB 683/4885ALDH1A1 217/4885 |
| US-20240423894-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | PRKDC, POLR1C, NACA | MAOA 391/4885MAOB 973/4885ALDH1A1 2928/4885 |
| US-20250352452-A1 | CLEAVABLE COMONOMER STRATEGY FOR ACCELERATING REMOVAL OF GEL NAIL POLISH | PRKDC, POLR1C, NACA | MAOA 391/4885MAOB 973/4885ALDH1A1 2928/4885 |
| US-20040102513-A1 | 2'-Substituted 1,1'-biphenyl-2-carboxamides, processes for their preparation, their use as medicaments, and pharmaceutical preparations comprising them | MLLT3, RYR2, CACNA1E | MAOA 981/4885MAOB 702/4885ALDH1A1 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.