Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 7/20 | 0.59 |
| ▸ | MAOB | P27338 | 7/20 | 0.59 |
| ▸ | PRF1 | P14222 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365201 | 1.00 | MAPT (0.61) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL30132801 | 0.84 | MAOB (0.62) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL856120 | 0.84 | MAOB (0.62) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL25386333 | 0.83 | MAOB (0.54) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL13932273 | 0.81 | SRD5A1 (0.44) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL25386767 | 0.80 | MAOB (0.61) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL31470976 | 0.80 | MAOB (0.61) | MAPTLMNAGAAMAOAMAOB | |
| SCHEMBL4043697 | 0.78 | MAPK14 (0.56) | — | |
| SCHEMBL14559426 | 0.78 | MAPK14 (0.60) | MAPTGAAMAOAMAOBALDH1A1 | |
| SCHEMBL10554226 | 0.77 | ALDH1A1 (0.53) | MAPTGAAMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120157657-A | Phthalazinone compound containing piperazinone, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2025-06-17 | — | — | CN | disclosed |