Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.65 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MMP7 | P09237 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413069 | 0.81 | HSD11B1 (0.70) | HSD11B1MMP2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL30121385 | 0.81 | HSD11B1 (0.70) | HSD11B1MMP2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL18381180 | 0.80 | HSD11B1 (0.77) | HSD11B1L3MBTL1MCOLN3MEN1ALDH1A1 | |
| SCHEMBL4405981 | 0.80 | HSD11B1 (0.69) | HSD11B1MMP1MMP3MMP7MMP2 | |
| SCHEMBL12786753 | 0.79 | HSD11B1 (1.00) | HSD11B1ALDH1A1LMNA | |
| SCHEMBL12786804 | 0.79 | HSD11B1 (1.00) | HSD11B1ALDH1A1LMNA | |
| SCHEMBL31471935 | 0.79 | HSD11B1 (0.67) | HSD11B1MMP1MMP3MMP13MMP2 | |
| SCHEMBL31471931 | 0.78 | HSD11B1 (0.67) | HSD11B1L3MBTL1ALDH1A1LMNAHTT | |
| SCHEMBL4403548 | 0.76 | HSD11B1 (0.64) | HSD11B1MMP3L3MBTL1 | |
| SCHEMBL1618372 | 0.74 | HSD11B1 (0.61) | HSD11B1MCOLN3MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025100889-A1 | QUINAZOLINE DERIVATIVE, SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2025-05-15 | — | — | WO | disclosed |