Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3155882 | 0.91 | FFAR4 (0.36) | EGLN1FFAR4CYP4A11CYP4F2 | |
| SCHEMBL3147340 | 0.89 | MAP4K4 (0.37) | ABL1EGLN1FFAR4P2RX7 | |
| SCHEMBL3137015 | 0.89 | ABL1 (0.37) | ABL1EGLN1CYP4A11 | |
| SCHEMBL3256998 | 0.88 | FFAR4 (0.42) | EGLN1FFAR4P2RX7 | |
| SCHEMBL3141819 | 0.87 | EGLN1 (0.48) | EGLN1 | |
| SCHEMBL3147035 | 0.83 | ABL1 (0.34) | ABL1FFAR4 | |
| Hydrochloric Acid SCHEMBL3781375 | 0.82 | ABL1 (0.34) | ABL1 | |
| SCHEMBL3147365 | 0.82 | ABL1 (0.37) | ABL1 | |
| SCHEMBL3772525 | 0.81 | ABL1 (0.34) | ABL1FFAR4DGAT1 | |
| SCHEMBL3151015 | 0.81 | FFAR4 (0.40) | EGLN1FFAR4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |