Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21491112 | 1.00 | LMNA (0.40) | LMNAPTGS2MEN1KMT2ASLC6A2 | |
| SCHEMBL29456428 | 0.90 | LMNA (0.37) | LMNAPTGS2MEN1KMT2ASLC6A2 | |
| SCHEMBL21491209 | 0.90 | LMNA (0.37) | LMNAPTGS2MEN1KMT2ASLC6A2 | |
| SCHEMBL29849134 | 0.90 | LMNA (0.37) | LMNAPTGS2MEN1KMT2ASLC6A2 | |
| SCHEMBL23036784 | 0.87 | SLC6A4 (0.41) | LMNAKMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21491442 | 0.82 | PTGS2 (0.36) | PTGS2PTGS1 | |
| SCHEMBL29456672 | 0.82 | PTGS2 (0.36) | PTGS2PTGS1 | |
| SCHEMBL24654621 | 0.82 | PTGS2 (0.36) | PTGS2PTGS1 | |
| SCHEMBL31472308 | 0.82 | PTGS2 (0.36) | PTGS2PTGS1 | |
| SCHEMBL21491170 | 0.82 | GAA (0.41) | SLC6A2SLC6A4SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236428-B | Antiproliferative compounds and uses thereof | 默克专利股份有限公司 | 2025-04-01 | — | — | CN | disclosed |