Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.36 |
| ▸ | PNMT | P11086 | 3/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24654621 | 1.00 | PTGS2 (0.36) | PTGS2PNMTSLC6A9PIM1PIM2 | |
| SCHEMBL29456672 | 1.00 | PTGS2 (0.36) | PTGS2PNMTSLC6A9PIM1PIM2 | |
| SCHEMBL21491442 | 1.00 | PTGS2 (0.36) | PTGS2PNMTSLC6A9PIM1PIM2 | |
| SCHEMBL21491209 | 0.85 | LMNA (0.37) | PTGS2PNMTPTGS1 | |
| SCHEMBL29849134 | 0.85 | LMNA (0.37) | PTGS2PNMTPTGS1 | |
| SCHEMBL29456428 | 0.85 | LMNA (0.37) | PTGS2PNMTPTGS1 | |
| SCHEMBL21491112 | 0.82 | LMNA (0.40) | PTGS2PTGS1 | |
| SCHEMBL31472349 | 0.82 | LMNA (0.40) | PTGS2PTGS1 | |
| SCHEMBL21491474 | 0.71 | RORC (0.36) | PTGS2SLC6A9DPP4PTGS1ATR | |
| SCHEMBL31472445 | 0.71 | RORC (0.36) | PTGS2SLC6A9DPP4PTGS1ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236428-B | Antiproliferative compounds and uses thereof | 默克专利股份有限公司 | 2025-04-01 | — | — | CN | disclosed |