Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21491130 | 1.00 | CFB (0.38) | CFBPTGS2MEN1KMT2ACHRM2 | |
| SCHEMBL29456508 | 1.00 | CFB (0.38) | CFBPTGS2MEN1KMT2ACHRM2 | |
| SCHEMBL21491186 | 0.84 | TSHR (0.41) | ALDH1A1 | |
| SCHEMBL29849328 | 0.84 | TSHR (0.41) | ALDH1A1 | |
| SCHEMBL23036825 | 0.84 | TSHR (0.41) | ALDH1A1 | |
| SCHEMBL3715027 | 0.75 | OPRM1 (0.39) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL21516196 | 0.72 | CRHBP (0.43) | CFBPTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL29456476 | 0.72 | CRHBP (0.43) | CFBPTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL23036742 | 0.72 | CRHBP (0.43) | CFBPTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL21491399 | 0.70 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236428-B | Antiproliferative compounds and uses thereof | 默克专利股份有限公司 | 2025-04-01 | — | — | CN | disclosed |