Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3147267 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| Hydrochloric Acid SCHEMBL9900831 | 0.74 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| Hydrochloric Acid SCHEMBL442699 | 0.73 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2POLBMAPT | |
| Hydrochloric Acid SCHEMBL14777373 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL1697483 | 0.68 | MAPT (0.34) | ALDH1A1SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL29364506 | 0.66 | SMN1; SMN2 (0.77) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL5318298 | 0.66 | SMN1; SMN2 (0.77) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL38838 | 0.66 | SMN1; SMN2 (0.77) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL31217637 | 0.66 | SMN1; SMN2 (0.95) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| Hydrochloric Acid SCHEMBL1609624 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1582534-B1 | Olefin polymerization catalyst and polymerization process | ROHM & HAAS (US) | 2010-02-10 | — | — | EP | disclosed |
| US-7098278-B2 | Olefin polymerization catalyst and polymerization process | ROHM AND HAAS COMPANY (US) | 2006-08-29 | — | — | US | disclosed |
| US-20060128911-A1 | Olefin polymerization catalyst and polymerization process | GOODALL BRIAN L | 2006-06-15 | — | — | US | disclosed |
| US-7037987-B2 | Olefin polymerization catalyst and polymerization process | ROHN AND HAAS COMPANY (US) | 2006-05-02 | — | — | US | disclosed |
| EP-1582534-A1 | Olefin polymerization catalyst and polymerization process | ROHM AND HAAS COMPANY (US) | 2005-10-05 | — | — | EP | disclosed |
| US-20050215738-A1 | Olefin polymerization catalyst and polymerization process | ROHM AND HAAS COMPANY | 2005-09-29 | — | — | US | disclosed |