SCHEMBL31473145

SCHEMBL31473145

C[C@H]1C(=O)N(C)[C@@H](CO[Si](C)(C)C(C)(C)C)C(=O)N1C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DUT P33316 3/20 0.34
TOP2A P11388 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31473141 0.77 CAPN1 (0.35)
SCHEMBL30769573 0.76 DUT (0.31) DUT
SCHEMBL31473152 0.74 FKBP1A (0.39) TOP2A
SCHEMBL30769750 0.74 FKBP1A (0.39) TOP2A
SCHEMBL13435540 0.71 TOP2A (0.33) DUTTOP2A
SCHEMBL8826943 0.66 ADRA2C (0.42)
SCHEMBL13391600 0.66 ADRA2C (0.42)
SCHEMBL22029081 0.66 PDK2 (0.37) DUTTOP2A
SCHEMBL5676774 0.66 PDK2 (0.37) DUTTOP2A
SCHEMBL13613725 0.66 DUT (0.34) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119403810-A Compounds, pharmaceutical compositions containing them and their medical use for the treatment or prevention of vascular diseases 瓦斯塞拉股份有限公司 2025-02-07 CN disclosed