Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27295837 | 1.00 | MEN1 (0.51) | MEN1KMT2AALOX12CDC7SYK | |
| SCHEMBL22280459 | 0.83 | ALDH1A1 (0.48) | GRM5MAPK10LMNAABCG2ABCB1 | |
| SCHEMBL10549553 | 0.83 | ABCG2 (0.53) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL27303096 | 0.81 | GRM5 (0.46) | MEN1KMT2AGRM5MAPK10LMNA | |
| SCHEMBL27302921 | 0.78 | KDM4E (0.47) | NPC1RAB9AMAPK1 | |
| SCHEMBL13352440 | 0.78 | KDM4E (0.52) | CDC7SYKNPC1RAB9AMAPT | |
| SCHEMBL22265881 | 0.75 | HPGD (0.53) | MEN1KMT2ANPC1RAB9AMAPK10 | |
| SCHEMBL22575269 | 0.74 | CYP11B2 (0.50) | MEN1KMT2ALMNAABCG2ABCB1 | |
| SCHEMBL27302479 | 0.74 | MEN1 (0.54) | MEN1KMT2ASYKMAPK10MAPT | |
| SCHEMBL22266091 | 0.74 | EPHX2 (0.45) | SYKSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119866333-A | KIT inhibitors, compounds, pharmaceutical compositions, and methods of use thereof | 亚力维克希斯股份有限公司 | 2025-04-22 | — | — | CN | disclosed |