Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | RARG | P13631 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474132 | 0.84 | KDM4E (0.41) | RARBRARGKDM4EALDH1A1PKM | |
| SCHEMBL31474162 | 0.82 | RARB (0.38) | RARBRARGRARAPTGS1PTGS2 | |
| SCHEMBL22222146 | 0.75 | KDM4E (0.41) | RARBRARGKDM4EALDH1A1PKM | |
| SCHEMBL1018779 | 0.74 | RARB (0.58) | RARBRARGKDM4EALDH1A1RARA | |
| SCHEMBL16744298 | 0.74 | RARB (0.73) | RARBRARGKDM4EALDH1A1RARA | |
| SCHEMBL31474080 | 0.72 | RXRA (0.42) | RARBRARGALDH1A1PKMRARA | |
| SCHEMBL522786 | 0.72 | CA12 (0.47) | KDM4EALDH1A1POLBMAPTTSHR | |
| SCHEMBL31474193 | 0.71 | RARB (0.39) | RARBRARGKDM4EALDH1A1PTGS1 | |
| SCHEMBL24469644 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1PKMMEN1KMT2A | |
| SCHEMBL29588474 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |