Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.42 |
| ▸ | RARG | P13631 | 5/20 | 0.42 |
| ▸ | RARB | P10826 | 4/20 | 0.42 |
| ▸ | RARA | P10276 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | RXRG | P48443 | 3/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474036 | 0.85 | SYK (0.35) | RXRARARGRARBRARAPIN1 | |
| SCHEMBL31474238 | 0.82 | RXRA (0.43) | RXRARARGRARBRARARXRB | |
| SCHEMBL17276295 | 0.82 | RARG (0.42) | RXRARARGRARBRARACYP3A4 | |
| SCHEMBL883735 | 0.74 | RAB9A (0.42) | PKMALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL31474057 | 0.74 | PKM (0.36) | RXRARARGRARBRARASYK | |
| SCHEMBL1496061 | 0.73 | CYP3A4 (0.40) | RXRACYP3A4PIN1 | |
| SCHEMBL522786 | 0.73 | CA12 (0.47) | ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL1496245 | 0.73 | CYP19A1 (0.38) | RXRARARGRARBRARACYP3A4 | |
| SCHEMBL31473996 | 0.72 | RARB (0.47) | RXRARARGRARBRARAPKM | |
| SCHEMBL8045039 | 0.71 | RARB (0.35) | RXRARARGRARBRARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |