Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | RARG | P13631 | 5/20 | 0.38 |
| ▸ | RARA | P10276 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 4/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31473996 | 0.82 | RARB (0.47) | RARBRARGRARAPTGS1PTGS2 | |
| SCHEMBL31474238 | 0.71 | RXRA (0.43) | RARBRARGRARAROCK2RXRA | |
| SCHEMBL31474213 | 0.70 | PARP1 (0.38) | PTGS1PTGS2DGAT1PARP1GRM2 | |
| SCHEMBL29706809 | 0.68 | MAP3K5 (0.44) | RARBRARGRARAROCK2RXRA | |
| SCHEMBL811340 | 0.68 | DGAT1 (0.58) | ROCK2DGAT1PARP1 | |
| SCHEMBL31474132 | 0.67 | KDM4E (0.41) | RARBRARG | |
| SCHEMBL31474125 | 0.67 | IRAK4 (0.44) | ROCK2DGAT1 | |
| SCHEMBL23011980 | 0.66 | MAP3K5 (0.46) | RARBRARGRARAROCK2RXRA | |
| SCHEMBL29177374 | 0.66 | KMT2A (0.42) | RARBRARGRARAPTGS1PTGS2 | |
| SCHEMBL21845248 | 0.66 | PARP1 (0.49) | PTGS1PTGS2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |