Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474150 | 0.86 | CA12 (0.34) | LMNAALDH1A1MAPTNPC1KDM4E | |
| SCHEMBL10858004 | 0.84 | LMNA (0.46) | LMNAALDH1A1MAPTPKMNPSR1 | |
| SCHEMBL10858754 | 0.83 | LMNA (0.45) | LMNAALDH1A1MAPTPKMNPSR1 | |
| SCHEMBL31474106 | 0.82 | ALDH1A1 (0.43) | LMNAALDH1A1MAPTPKMNPSR1 | |
| SCHEMBL7113958 | 0.81 | LMNA (0.43) | LMNAALDH1A1MAPTPKMNPSR1 | |
| SCHEMBL6612160 | 0.79 | LMNA (0.59) | LMNAALDH1A1MAPTPKMNPSR1 | |
| SCHEMBL31474062 | 0.77 | FFAR4 (0.39) | LMNAALDH1A1MAPTNPSR1NPC1 | |
| SCHEMBL12035930 | 0.77 | ALDH1A1 (0.39) | LMNAALDH1A1MAPTPKMNPSR1 | |
| SCHEMBL7060849 | 0.76 | LMNA (0.42) | LMNAALDH1A1MAPTPKMNPSR1 | |
| SCHEMBL644841 | 0.75 | CA12 (0.36) | LMNAALDH1A1MAPTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |