SCHEMBL644841

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL643701	0.78	ALDH1A1 (0.38)	CA12CA1CA2CA7CA9
	SCHEMBL644768	0.78	CA12 (0.36)	CA12CA1CA2CA7CA9
	SCHEMBL22032240	0.76	CA12 (0.41)	CA12CA1CA2CA7CA9
	SCHEMBL31474073	0.75	LMNA (0.45)	ALDH1A1MAPTLMNARAB9ANPSR1
	SCHEMBL12035930	0.75	ALDH1A1 (0.39)	CA12CA1CA2CA7CA9
	SCHEMBL642494	0.74	SCN9A (0.39)	—
	SCHEMBL31474062	0.72	FFAR4 (0.39)	CA12CA1CA2CA7CA9
	SCHEMBL12035940	0.72	FFAR4 (0.43)	ALDH1A1MAPTLMNATSHRSMN1; SMN2
	SCHEMBL25318072	0.72	ALDH1A1 (0.37)	ALDH1A1MAPTLMNAGAAFFAR4
	SCHEMBL642488	0.72	GCK (0.46)	ALDH1A1MAPTKDM4EPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.