Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618233 | 0.79 | KDM4E (0.50) | MAPK1SOS1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1018163 | 0.75 | NOTUM (0.44) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL31474107 | 0.75 | MAOB (0.47) | MAPK1TSHRHSD17B10TDP1NPC1 | |
| SCHEMBL17670781 | 0.75 | TDP1 (0.47) | SMN1; SMN2MAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL3629768 | 0.75 | NOTUM (0.48) | PKMSMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL29116901 | 0.75 | ALDH1A1 (0.44) | PKMSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL24502934 | 0.74 | FFAR4 (0.49) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL20775395 | 0.74 | SOS1 (0.40) | PKMSOS1MEN1KMT2AKDM4E | |
| SCHEMBL1044961 | 0.74 | SOS1 (0.46) | PKMSOS1KDM4EALDH1A1TSHR | |
| SCHEMBL7881748 | 0.73 | PKM (0.43) | PKMSMN1; SMN2MAPK1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |