SCHEMBL31474155

SCHEMBL31474155

[2H]C([2H])([2H])N(CCO[Si](C)(C)C(C)(C)C)C(=O)OCc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
BTN3A1 O00481 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CCR6 P51684 1/20 0.37
PAX8 Q06710 1/20 0.37
L3MBTL1 Q9Y468 3/20 0.36
SIGMAR1 Q99720 1/20 0.36
MAPK1 P28482 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KMT2A Q03164 1/20 0.35
F13A1 P00488 1/20 0.35
TGM2 P21980 1/20 0.35
TGM1 P22735 1/20 0.35
HDAC1 Q13547 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31447906 0.85 CCR6 (0.48) ALDH1A1BTN3A1SMN1; SMN2CCR6PAX8
SCHEMBL1896284 0.84 ALDH1A1 (0.40) ALDH1A1BTN3A1SMN1; SMN2CCR6PAX8
SCHEMBL7270408 0.81 CCR6 (0.47) ALDH1A1BTN3A1SMN1; SMN2CCR6PAX8
SCHEMBL30510995 0.81 CCR6 (0.42) ALDH1A1BTN3A1SMN1; SMN2CCR6PAX8
SCHEMBL25346091 0.81 CCR6 (0.42) ALDH1A1BTN3A1SMN1; SMN2CCR6PAX8
SCHEMBL30510994 0.80 L3MBTL1 (0.41) ALDH1A1BTN3A1CCR6PAX8L3MBTL1
SCHEMBL4558309 0.78 ALDH1A1 (0.41) ALDH1A1BTN3A1SMN1; SMN2CCR6PAX8
SCHEMBL25344309 0.78 L3MBTL1 (0.41) ALDH1A1BTN3A1CCR6PAX8L3MBTL1
SCHEMBL31473983 0.78 ALDH1A1 (0.49) ALDH1A1CCR6PAX8L3MBTL1SIGMAR1
SCHEMBL5724513 0.77 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2CCR6PAX8L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025061148-A1 HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE 江苏恒瑞医药股份有限公司 2025-03-27 WO disclosed