Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30510994 | 0.96 | L3MBTL1 (0.41) | L3MBTL1CCR6PAX8GBA1HTR2C | |
| SCHEMBL25346091 | 0.90 | CCR6 (0.42) | L3MBTL1CCR6PAX8F13A1TGM2 | |
| SCHEMBL31447906 | 0.89 | CCR6 (0.48) | L3MBTL1CCR6PAX8ALDH1A1BTN3A1 | |
| SCHEMBL25977140 | 0.85 | GBA1 (0.40) | L3MBTL1GBA1HTR2CSLC6A4GLS | |
| SCHEMBL7270408 | 0.85 | CCR6 (0.47) | L3MBTL1CCR6PAX8ALDH1A1BTN3A1 | |
| SCHEMBL30311467 | 0.83 | CCR6 (0.48) | L3MBTL1CCR6PAX8GBA1HTR2C | |
| SCHEMBL25970374 | 0.83 | CCR6 (0.45) | L3MBTL1CCR6PAX8GBA1HTR2C | |
| SCHEMBL19700749 | 0.82 | L3MBTL1 (0.45) | L3MBTL1CCR6PAX8GBA1HTR2C | |
| SCHEMBL7775544 | 0.82 | L3MBTL1 (0.50) | L3MBTL1CCR6PAX8GBA1HTR2C | |
| SCHEMBL1896284 | 0.81 | ALDH1A1 (0.40) | L3MBTL1CCR6PAX8F13A1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257396-A1 | MACROCYCLES AND THEIR USE | BLOSSOMHILL THERAPEUTICS INC (US) | 2023-08-17 | — | — | US | disclosed |
| EP-4178958-A1 | MACROCYCLES AND THEIR USE | Blossomhill Therapeutics, Inc. (US) | 2023-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257396-A1 | MACROCYCLES AND THEIR USE | VHL, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DLD | L3MBTL1 3134/4885CCR6 927/4885PAX8 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.