SCHEMBL31474196

SCHEMBL31474196

Clc1cc2c(cn1)-c1ccncc1OC2

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 3/20 0.46
ROCK2 O75116 17/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31474211 0.82 AAK1 (0.49) AAK1ROCK2
SCHEMBL31627348 0.82 AAK1 (0.46) AAK1ROCK2
SCHEMBL19946104 0.80 ROCK2 (0.56) AAK1ROCK2
SCHEMBL31627499 0.78 AAK1 (0.49) AAK1ROCK2
SCHEMBL31474318 0.76 AAK1 (0.42) AAK1ROCK2
SCHEMBL31468765 0.74 AAK1 (0.53) AAK1ROCK2
SCHEMBL31468763 0.74 ROCK2 (0.50) AAK1ROCK2
SCHEMBL18901287 0.74 AAK1 (0.53) AAK1ROCK2
SCHEMBL11558683 0.74 ROCK2 (0.49) AAK1ROCK2
SCHEMBL15240901 0.71 ROCK2 (0.61) AAK1ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025128834-A1 AKT1 MODULATORS ALTEROME THERAPEUTICS, INC. (US) 2025-06-19 WO disclosed
WO-2025060978-A1 TRICYCLIC PYRIDINE COMPOUND ACTING AS SARM1 ENZYME ACTIVITY INHIBITOR, AND USE THEREOF 科辉智药(深圳)新药研究中心有限公司 2025-03-27 WO disclosed