Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 16/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31468772 | 0.80 | ROCK2 (0.55) | AAK1ROCK2ROCK1 | |
| SCHEMBL31627348 | 0.76 | AAK1 (0.46) | AAK1ROCK2ROCK1 | |
| SCHEMBL31474211 | 0.76 | AAK1 (0.49) | AAK1ROCK2ROCK1 | |
| SCHEMBL31474196 | 0.76 | AAK1 (0.46) | AAK1ROCK2 | |
| SCHEMBL31474217 | 0.75 | ROCK2 (0.44) | AAK1ROCK2 | |
| SCHEMBL31627499 | 0.73 | AAK1 (0.49) | AAK1ROCK2ROCK1 | |
| SCHEMBL18901287 | 0.69 | AAK1 (0.53) | AAK1ROCK2ROCK1 | |
| SCHEMBL19946104 | 0.69 | ROCK2 (0.56) | AAK1ROCK2 | |
| SCHEMBL31468765 | 0.69 | AAK1 (0.53) | AAK1ROCK2ROCK1 | |
| SCHEMBL31468763 | 0.69 | ROCK2 (0.50) | AAK1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025060978-A1 | TRICYCLIC PYRIDINE COMPOUND ACTING AS SARM1 ENZYME ACTIVITY INHIBITOR, AND USE THEREOF | 科辉智药(深圳)新药研究中心有限公司 | 2025-03-27 | — | — | WO | disclosed |