Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474206 | 0.93 | CCR3 (0.40) | ROCK2TP53CCR3PDE4APDE4B | |
| SCHEMBL31300153 | 0.88 | TSHR (0.45) | TP53PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31300138 | 0.88 | PDE4A (0.41) | TP53PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27504767 | 0.88 | STS (0.48) | LMNAGPR119 | |
| SCHEMBL3741416 | 0.88 | STS (0.48) | LMNAGPR119 | |
| SCHEMBL31300148 | 0.85 | HDAC1 (0.53) | TP53PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31300149 | 0.85 | HDAC1 (0.53) | TP53PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31021788 | 0.84 | PDE4A (0.40) | TP53PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31021748 | 0.84 | OPRK1 (0.39) | TP53CCR3PDE4APDE4BPDE4C | |
| SCHEMBL31300128 | 0.81 | GABRA5 (0.40) | TP53PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025060978-A1 | TRICYCLIC PYRIDINE COMPOUND ACTING AS SARM1 ENZYME ACTIVITY INHIBITOR, AND USE THEREOF | 科辉智药(深圳)新药研究中心有限公司 | 2025-03-27 | — | — | WO | disclosed |