Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31300177 | 0.93 | MEN1 (0.44) | TSHRMEN1KMT2ANPSR1VEGFA | |
| SCHEMBL31300138 | 0.88 | PDE4A (0.41) | STSPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31474233 | 0.88 | ROCK2 (0.43) | MEN1KMT2ALMNAPDE4APDE4B | |
| SCHEMBL27504767 | 0.88 | STS (0.48) | STSLMNA | |
| SCHEMBL3741416 | 0.88 | STS (0.48) | STSLMNA | |
| SCHEMBL31300148 | 0.85 | HDAC1 (0.53) | STSSMN1; SMN2LMNAALDH1A1PDE4A | |
| SCHEMBL31300149 | 0.85 | HDAC1 (0.53) | STSSMN1; SMN2LMNAALDH1A1PDE4A | |
| SCHEMBL31021748 | 0.84 | OPRK1 (0.39) | STSPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15561496 | 0.82 | TSHR (0.44) | TSHRMEN1KMT2ANPSR1VEGFA | |
| SCHEMBL31300128 | 0.81 | GABRA5 (0.40) | STSPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737448-A1 | SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF | Artivila (ShenZhen) Innovation Center, Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025060978-A1 | TRICYCLIC PYRIDINE COMPOUND ACTING AS SARM1 ENZYME ACTIVITY INHIBITOR, AND USE THEREOF | 科辉智药(深圳)新药研究中心有限公司 | 2025-03-27 | — | — | WO | disclosed |
| WO-2025002030-A1 | SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF | 科辉智药(深圳)新药研究中心有限公司 | 2025-01-02 | — | — | WO | disclosed |