Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29503193 | 0.87 | PRSS1 (0.53) | TSHRPRSS1PRSS2PRSS3KDM1A | |
| SCHEMBL16742350 | 0.81 | PRSS1 (0.51) | TSHRPRSS1PRSS2PRSS3KDM1A | |
| SCHEMBL28157952 | 0.81 | TSHR (0.51) | TSHRKDM1ANPC1CASP3RAB9A | |
| SCHEMBL30898683 | 0.78 | TDP2 (0.43) | TSHRPRSS1PRSS2PRSS3S1PR5 | |
| SCHEMBL30591591 | 0.72 | ALDH1A1 (0.40) | KDM1AS1PR5 | |
| SCHEMBL30344379 | 0.69 | TSHR (0.68) | TSHRKDM1ANPC1CASP3RAB9A | |
| SCHEMBL4320180 | 0.69 | TSHR (0.68) | TSHRKDM1ANPC1CASP3RAB9A | |
| SCHEMBL17444524 | 0.69 | KDM1A (0.43) | TSHRKDM1ASMN1; SMN2PDK2 | |
| SCHEMBL29501133 | 0.69 | TSHR (0.45) | TSHRPRSS1PRSS2PRSS3KDM1A | |
| SCHEMBL18133312 | 0.69 | NPC1 (0.53) | TSHRNPC1CASP3RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |