Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | PRF1 | P14222 | 1/20 | 0.38 |
| ▸ | STK4 | Q13043 | 1/20 | 0.38 |
| ▸ | STK3 | Q13188 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898666 | 0.78 | TDP2 (0.45) | TDP2PDK2ERN1PRF1STK4 | |
| SCHEMBL31474283 | 0.78 | TSHR (0.51) | PDK2TSHRPRSS1PRSS2PRSS3 | |
| SCHEMBL30898644 | 0.74 | TDP2 (0.43) | TDP2PDK2ERN1PRF1STK4 | |
| SCHEMBL15451325 | 0.74 | TSHR (0.68) | TDP2ERN1PRF1TSHRGABRA1 | |
| SCHEMBL30898648 | 0.73 | MAPK14 (0.56) | TDP2 | |
| SCHEMBL30898657 | 0.72 | TDP2 (0.38) | TDP2PDK2ERN1STK4STK3 | |
| SCHEMBL30898661 | 0.72 | BRD4 (0.40) | TDP2PDK2ERN1STK4STK3 | |
| SCHEMBL30898614 | 0.72 | BRD4 (0.40) | TDP2PDK2ERN1STK4STK3 | |
| SCHEMBL980269 | 0.71 | GABRA1 (0.63) | ERN1HPGDTSHRGABRA1GABRB2 | |
| SCHEMBL30898718 | 0.70 | MAP3K14 (0.44) | TDP2NSD2PDK2ERN1PRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330008-B | Preparation method of amide compound and application of amide compound in medicine field | 上海华汇拓医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |