Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.30 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.30 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.30 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24809295 | 0.80 | RXRA (0.42) | RARBRARGRXRARARAKDM1A | |
| SCHEMBL4233044 | 0.78 | SIGMAR1 (0.37) | RXRA | |
| SCHEMBL1496245 | 0.78 | CYP19A1 (0.38) | RARBRARGRXRARARA | |
| SCHEMBL22589962 | 0.77 | ESR1 (0.35) | RARBRXRAKDM1A | |
| SCHEMBL17276260 | 0.76 | ABCC9 (0.39) | RARBRARGRXRARARAAKR1B1 | |
| SCHEMBL1496061 | 0.75 | CYP3A4 (0.40) | RXRA | |
| SCHEMBL1496260 | 0.74 | CYP19A1 (0.39) | RARBRARGRXRARARA | |
| SCHEMBL4808535 | 0.74 | BACE1 (0.30) | — | |
| SCHEMBL15717279 | 0.73 | RXRA (0.41) | RARBRARGRXRARARAKDM1A | |
| SCHEMBL1495945 | 0.73 | HTR2C (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |