Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26882627 | 1.00 | ALDH1A1 (0.67) | ALDH1A1HIF1ATDP1PTGS2LMNA | |
| SCHEMBL26882629 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HIF1ATDP1PTGS2LMNA | |
| SCHEMBL31474442 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HIF1ATDP1PTGS2LMNA | |
| SCHEMBL29095723 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HIF1ATDP1PTGS2LMNA | |
| SCHEMBL28654740 | 0.82 | PTGS2 (0.85) | ALDH1A1HIF1ATDP1PTGS2LMNA | |
| SCHEMBL26676662 | 0.82 | ALDH1A1 (0.75) | ALDH1A1HIF1ATDP1PTGS2LMNA | |
| SCHEMBL16797443 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HIF1ATDP1PTGS2LMNA | |
| SCHEMBL24470890 | 0.80 | PTGS2 (0.59) | ALDH1A1HIF1ATDP1PTGS2LMNA | |
| SCHEMBL29713132 | 0.80 | PTGS2 (0.59) | ALDH1A1HIF1ATDP1PTGS2LMNA | |
| SCHEMBL8324686 | 0.80 | CA12 (0.54) | ALDH1A1KDM4EMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403794-A | Novel derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2025-02-07 | — | — | CN | disclosed |