Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.54 |
| ▸ | CA9 | Q16790 | 5/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1390713 | 0.83 | CA12 (0.60) | CA12CA9CA1PIM1FLT3 | |
| SCHEMBL7795617 | 0.83 | PIM1 (0.60) | CA12CA9CA1PIM1FLT3 | |
| SCHEMBL8118515 | 0.82 | MAOB (0.55) | CA12CA9MAOBPIM1FLT3 | |
| SCHEMBL648621 | 0.82 | MAOB (0.70) | CA12CA9MAOBKDM4EALDH1A1 | |
| SCHEMBL6867907 | 0.81 | MAOB (0.54) | CA12CA9MAOBFLT3KDM4E | |
| SCHEMBL31474440 | 0.80 | ALDH1A1 (0.67) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL26882627 | 0.80 | ALDH1A1 (0.67) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL8328098 | 0.79 | CA12 (0.50) | CA12CA9CA1MAOBALDH1A1 | |
| SCHEMBL18591911 | 0.79 | MAOB (0.52) | CA12CA9CA1MAOBFLT3 | |
| SCHEMBL18611964 | 0.79 | MAOB (0.52) | CA12CA9CA1MAOBFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |