Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 4/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2351827 | 0.74 | CHRNB2 (0.41) | HRH4CHRNB2CHRNA4PRKD1PRKD2 | |
| SCHEMBL4060441 | 0.72 | HTR2C (0.43) | CHRNB2CHRNA4 | |
| SCHEMBL31398108 | 0.72 | CHRNB2 (0.48) | SYKCHRNB2CHRNA4 | |
| SCHEMBL26136470 | 0.71 | IKBKB (0.39) | HRH4CHRNB2CHRNA4PRKD1PRKD2 | |
| SCHEMBL19581178 | 0.70 | HTR2C (0.46) | SYKPRKD1PRKD2ADRB1PRKD3 | |
| SCHEMBL11678873 | 0.70 | ATR (0.46) | SYKJAK3BTKATR | |
| SCHEMBL24984228 | 0.69 | LMNA (0.40) | HRH4HRH3PRKD1PRKD2KCNH2 | |
| SCHEMBL31185490 | 0.69 | LMNA (0.40) | HRH4HRH3PRKD1PRKD2KCNH2 | |
| SCHEMBL28699019 | 0.68 | ACVR1 (0.44) | CHRNB2CHRNA4ADRB1IRAK4 | |
| Hydrochloric Acid SCHEMBL28856268 | 0.66 | PLAU (0.43) | KCNH2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403551-A | Small molecule inhibitors of TEA domain family members | 斯克里普斯研究学院 | 2025-02-07 | — | — | CN | disclosed |