SCHEMBL314751

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1303756	0.87	ATM (0.50)	POLBTDP1L3MBTL1CYP2C9MAPT
	SCHEMBL10250947	0.82	RAB9A (0.47)	POLBTDP1L3MBTL1CYP2C9CYP2C19
	SCHEMBL11300411	0.82	PTGS2 (0.50)	SMN1; SMN2POLBTDP1KDM4ENPC1
	SCHEMBL1303088	0.82	POLB (0.40)	POLBTDP1L3MBTL1CYP2C9CYP2C19
	SCHEMBL9779069	0.81	CYP1A2 (0.56)	SMN1; SMN2POLBTDP1CYP2C9CYP2C19
	SCHEMBL1303442	0.78	CYP1A2 (0.56)	SMN1; SMN2POLBTDP1L3MBTL1CYP2C19
	SCHEMBL1304185	0.77	SMN1; SMN2 (0.42)	SMN1; SMN2CYP26A1TDP1CYP2C9CYP2C19
	SCHEMBL2398084	0.75	L3MBTL1 (0.50)	L3MBTL1ALDH1A1MAPT
	SCHEMBL1303722	0.74	POLB (0.55)	SMN1; SMN2POLBMAPTKMT2A
	SCHEMBL5904628	0.73	ATM (0.51)	PDE4DNPC1ALDH1A1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.