SCHEMBL31475427

SCHEMBL31475427

CC(C)(C)OC(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)C(=O)NC1CCCC1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
EPHX1 P07099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30170007 0.96 CTSL (0.40)
SCHEMBL29015511 0.92 HDAC4 (0.39) HDAC4HDAC1HDAC6
SCHEMBL29015510 0.92 HDAC4 (0.39) HDAC4HDAC1HDAC6
SCHEMBL31475423 0.88 HDAC4 (0.41) HDAC4HDAC1HDAC6EPHX1
SCHEMBL24014368 0.87 CTSL (0.40)
SCHEMBL25650519 0.87 CTSL (0.40)
SCHEMBL29015517 0.85 CTSL (0.41)
SCHEMBL29015515 0.85 CTSL (0.41)
SCHEMBL30170256 0.84 CTSL (0.38) HDAC4HDAC1HDAC6
SCHEMBL26466628 0.84 CTSL (0.38) HDAC4HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025071482-A1 3CPRO INHIBITORS AND METHODS THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) (SG) 2025-04-03 WO disclosed