SCHEMBL752483

SCHEMBL752483

c1ccc(-c2ccc(-c3nc4ccccc4o3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.73
RAB9A P51151 5/20 0.73
MEN1 O00255 3/20 0.73
KMT2A Q03164 3/20 0.73
ATM Q13315 1/20 0.73
HSD17B10 Q99714 4/20 0.67
HPGD P15428 4/20 0.67
SMN1; SMN2 Q16637 4/20 0.67
ALDH1A1 P00352 3/20 0.67
KDM4E B2RXH2 3/20 0.67
TP53 P04637 1/20 0.67
MMP2 P08253 1/20 0.63
MMP9 P14780 1/20 0.63
MMP8 P22894 1/20 0.63
MMP13 P45452 1/20 0.63
MAPT P10636 2/20 0.59
PTPN2 P17706 1/20 0.59
PTPN1 P18031 1/20 0.59
PTPN5 P54829 1/20 0.59
CASP3 P42574 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27281692 1.00 NPC1 (0.73) NPC1RAB9AMEN1KMT2AATM
2-Phenylbenzo[D]Oxazole SCHEMBL27567766 0.96 NPC1 (0.72) NPC1RAB9AMEN1KMT2AATM
2-Phenylbenzo[D]Oxazole SCHEMBL31738605 0.96 NPC1 (0.72) NPC1RAB9AMEN1KMT2AATM
2-Phenylbenzo[D]Oxazole SCHEMBL395084 0.96 NPC1 (0.72) NPC1RAB9AMEN1KMT2AATM
2-Phenylbenzo[D]Oxazole SCHEMBL2458370 0.96 NPC1 (0.72) NPC1RAB9AMEN1KMT2AATM
2-Phenylbenzo[D]Oxazole SCHEMBL29819732 0.96 NPC1 (0.72) NPC1RAB9AMEN1KMT2AATM
2-Phenylbenzo[D]Oxazole SCHEMBL29767802 0.96 NPC1 (0.72) NPC1RAB9AMEN1KMT2AATM
SCHEMBL31476 0.96 NPC1 (0.79) NPC1RAB9AMEN1KMT2AATM
2-Phenylbenzo[D]Oxazole SCHEMBL127448 0.96 NPC1 (0.72) NPC1RAB9AMEN1KMT2AATM
SCHEMBL19846114 0.94 NPC1 (0.67) NPC1RAB9AMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142329-A1 ORGANIC LIGHT EMITTING ELEMENT LG DISPLAY CO., LTD. (KR) 2023-05-11 US disclosed
EP-1245659-B2 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL CO (JP) 2020-03-11 EP disclosed
US-10141513-B2 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-11-27 US disclosed
US-8993777-B2 Method for producing phenyl-substituted heterocyclic derivative NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2015-03-31 US disclosed
US-8993777-B2 Method for producing phenyl-substituted heterocyclic derivative NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2015-03-31 US disclosed
US-20140275549-A1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-09-18 US disclosed
US-20140275549-A1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-09-18 US disclosed
US-20140183508-A1 POLYMERIC LIGHT EMITTING SUBSTANCE AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-03 US disclosed
EP-2258805-B1 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL CO (JP) 2013-10-30 EP disclosed
US-8492007-B2 Metal complex and organic electroluminescent device SUMITOMO CHEMICAL COMPANY (JP) 2013-07-23 US disclosed
US-20050147843-A1 carbazole phenylpyridine metal complexes or conjugated with additional polymers, for use in a light-emitting device; light emission from triplet excited state SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-07 US disclosed
EP-1032850-B1 SELF-SCINTILLATING SHEET MATERIAL FOR RADIOACTIVE SPECIES ANALYSIS MINNESOTA MINING & MFG (US) 2003-12-17 EP disclosed
US-20020193532-A1 Comprises polystyrene and organometallic polymer; luminescence; for use in spin coating and ink jet printing SUMITOMO CHEMICAL COMPANY, LIMITED 2002-12-19 US disclosed
EP-1245659-A1 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-02 EP disclosed
EP-1183554-A1 IN-SITU RADIOACTIVITY DETECTION 3M Innovative Properties Company (US) 2002-03-06 EP disclosed
WO-2000077545-A1 IN-SITU RADIOACTIVITY DETECTION 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-21 WO disclosed
US-6139749-A CONTACTING ENVIRONMENTAL FLUID WITH COMPOSITE SHEET MATERIAL COMPRISING SEPARATORS AND SCINTILLATORS ENTRAPPED IN POROUS MATRIX OR MEMBRANE 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-10-31 US disclosed
EP-1032850-A1 SELF-SCINTILLATING SHEET MATERIAL FOR RADIOACTIVE SPECIES ANALYSIS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-09-06 EP disclosed
WO-1999027387-A1 SELF-SCINTILLATING SHEET MATERIAL FOR RADIOACTIVE SPECIES ANALYSIS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-03 WO disclosed
EP-0479161-A1 Synthesis of heterocyclic compounds EASTMAN CHEMICAL COMPANY (US) 1992-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140275549-A1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE PAH, DDT, NISCH NPC1 1346/4885RAB9A 2878/4885MEN1 338/4885
US-20230142329-A1 ORGANIC LIGHT EMITTING ELEMENT L3MBTL3, L3MBTL4, CRY2 NPC1 3736/4885RAB9A 3651/4885MEN1 1316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.