Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.59 |
| ▸ | MMP2 | P08253 | 2/20 | 0.59 |
| ▸ | MMP9 | P14780 | 2/20 | 0.59 |
| ▸ | MMP12 | P39900 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | AGXT | P21549 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31326237 | 0.88 | MMP1 (0.61) | MMP1MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL28556983 | 0.88 | MMP1 (0.61) | MMP1MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL31083932 | 0.86 | MMP1 (0.59) | MMP1MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL10351327 | 0.86 | CYP3A4 (0.61) | MMP1MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL6709375 | 0.85 | ALDH1A1 (0.73) | ALDH1A1RAB9AMAOBKMT2AKDM4E | |
| SCHEMBL6139463 | 0.85 | IDO1 (0.62) | MMP1MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL5526159 | 0.85 | MMP1 (0.58) | MMP1MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL30486011 | 0.84 | MMP1 (0.54) | MMP1MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL11740929 | 0.84 | NPC1 (0.55) | MMP1MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL5072089 | 0.84 | MMP1 (0.54) | MMP1MMP2MMP9MMP12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260185-A | Deuterated derivatives of corydaline and stepholidine and preparation method thereof | 杨征 | 2022-11-01 | — | — | CN | disclosed |
| EP-3122749-B1 | PROCESS FOR PREPARING A CARBAPENEM ANTIBIOTIC | JOHNSON MATTHEY PLC (GB) | 2019-03-13 | — | — | EP | disclosed |
| CN-108617166-A | Protein Kinase Inhibitor Benzolactam Compounds | 大冢制药株式会社 | 2018-10-02 | — | — | CN | disclosed |
| US-20170210744-A1 | PROCESS FOR PREPARING A CARBAPENEM ANTIBIOTIC | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2017-07-27 | — | — | US | disclosed |
| WO-2015145161-A1 | PROCESS FOR PREPARING A CARBAPENEM ANTIBIOTIC | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2015-10-01 | — | — | WO | disclosed |
| WO-2014169817-A1 | PHENYLALANINE COMPOUND HAVING NITROGEN HETEROCYCLIC LINK, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国科学院上海药物研究所 (CN) | 2014-10-23 | — | — | WO | disclosed |
| EP-2125683-B1 | 3-BENZOFURANYL-4-INDOLYL-MALEIMIDES AS POTENT GSK-3 INHIBITORS FOR NEURODEGENERATIVE DISORDERS | UNIV ILLINOIS (US) | 2013-10-23 | — | — | EP | disclosed |
| EP-2631238-A1 | Spirocyclic inhibitors of serine proteases for the treatment of hcv infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-08-28 | — | — | EP | disclosed |
| US-8207216-B2 | Benzofuran-3-yl(indol-3-yl) maleimides as potent GSK3 inhibitors | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-06-26 | — | — | US | disclosed |
| US-8207216-B2 | Benzofuran-3-yl(indol-3-yl) maleimides as potent GSK3 inhibitors | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-06-26 | — | — | US | disclosed |
| US-7544706-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-09 | — | — | US | disclosed |
| US-20080293727-A1 | Novel sulfonamide inhibitors of aspartyl protease | TUNG ROGER D | 2008-11-27 | — | — | US | disclosed |
| WO-2008077138-A1 | 3-BENZOFURANYL-4-INDOLYL MALEIMIDES AS POTENT GSK3 INHIBITORS FOR NEUROGENERATIVE DISORDERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-06-26 | — | — | WO | disclosed |
| US-20080125473-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-29 | — | — | US | disclosed |
| US-20080119536-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-22 | — | — | US | disclosed |
| US-7321063-B2 | Sulfonamide inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-01-22 | — | — | US | disclosed |
| US-20070167506-A1 | SUBSTITUTED IMIDAZOLES | PFIZER INC. (US) | 2007-07-19 | — | — | US | disclosed |
| US-5354919-A | Catalyzing with an oxidizers in an aqueous solution and a solid palladium-containing oxidation catalysts | RHONE-POULENC CHIMIE (FR) | 1994-10-11 | — | — | US | disclosed |
| EP-0577476-A1 | Process for the oxidation of aromatic compounds containing an oxidisable alkyl group | RHONE-POULENC CHIMIE (FR) | 1994-01-05 | — | — | EP | disclosed |
| US-4513001-A | β-Adrenergic 1-[1-benzimidazolyl]-N-[2-(4-hydroxy-3-methoxy-phenyl)-2-hydroxy-ethyl]-3-amino butane and salts and hydrates thereof | LABORATOIRE ROGER BELLON (FR) | 1985-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125473-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | MMP1 2571/4885MMP2 3529/4885MMP9 3497/4885 |
| US-20170210744-A1 | PROCESS FOR PREPARING A CARBAPENEM ANTIBIOTIC | MGAM, HAMP, MB | MMP1 2042/4885MMP2 1988/4885MMP9 662/4885 |
| US-20070167506-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | MMP1 2571/4885MMP2 3529/4885MMP9 3497/4885 |
| US-20080119536-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | MMP1 2571/4885MMP2 3529/4885MMP9 3497/4885 |
| US-20080293727-A1 | Novel sulfonamide inhibitors of aspartyl protease | SPINT2, PRSS1, DNPEP | MMP1 808/4885MMP2 484/4885MMP9 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.