Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 11/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 8/20 | 0.52 |
| ▸ | DRD3 | P35462 | 6/20 | 0.49 |
| ▸ | HTR2A | P28223 | 5/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147702 | 1.00 | BDKRB1 (0.61) | BDKRB1KCNH2DRD2DRD3HTR2A | |
| SCHEMBL3049816 | 0.92 | BDKRB1 (0.56) | BDKRB1KCNH2DRD2 | |
| SCHEMBL3049821 | 0.92 | BDKRB1 (0.56) | BDKRB1KCNH2DRD2 | |
| SCHEMBL3140960 | 0.87 | DRD2 (0.49) | BDKRB1KCNH2DRD2DRD3HTR2A | |
| SCHEMBL3140964 | 0.87 | DRD2 (0.49) | BDKRB1KCNH2DRD2DRD3HTR2A | |
| SCHEMBL3149091 | 0.86 | DRD2 (0.48) | BDKRB1KCNH2DRD2DRD3HTR2A | |
| SCHEMBL3149096 | 0.86 | DRD2 (0.48) | BDKRB1KCNH2DRD2DRD3HTR2A | |
| SCHEMBL3274490 | 0.85 | BDKRB1 (0.57) | BDKRB1KCNH2 | |
| SCHEMBL3157840 | 0.81 | CCR2 (0.47) | DRD2DRD3HTR2A | |
| SCHEMBL3157834 | 0.81 | CCR2 (0.47) | DRD2DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074083-B1 | NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2013-06-19 | — | — | EP | disclosed |
| US-20100075978-A1 | SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075978-A1 | SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | BDKRB1, BDKRB2, TRPV1 | BDKRB1 1/4885KCNH2 80/4885DRD2 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.