Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31477128 | 0.87 | CNR1 (0.41) | ACHECES2NPSR1L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31477592 | 0.86 | CNR1 (0.40) | ACHECES2NPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL2158786 | 0.77 | RXRA (0.53) | ACHEHSD17B10KIF11 | |
| SCHEMBL31477048 | 0.76 | SLC7A5 (0.40) | — | |
| SCHEMBL31292467 | 0.74 | MAPT (0.53) | ACHEL3MBTL1TSHRHSD17B10TDP1 | |
| SCHEMBL7488968 | 0.74 | ATM (0.59) | L3MBTL1ALDH1A1HSD17B10TDP1MAPT | |
| Pivalate SCHEMBL31477388 | 0.74 | SLC7A5 (0.38) | — | |
| SCHEMBL9426280 | 0.72 | ACHE (0.48) | ACHEL3MBTL1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL31422399 | 0.72 | AKR1B1 (0.43) | AKR1C3AKR1C2ALDH1A1TSHRTDP1 | |
| SCHEMBL31422560 | 0.72 | AKR1B1 (0.43) | AKR1C3AKR1C2ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025085554-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |