Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27332603 | 0.79 | ACHE (0.56) | ACHETDP1MAPTL3MBTL1RXRA | |
| SCHEMBL29035792 | 0.75 | TDP1 (0.54) | ACHETDP1MAPTL3MBTL1RXRA | |
| SCHEMBL23772184 | 0.74 | ACHE (0.43) | ACHEL3MBTL1RXRARXRBCYP26A1 | |
| SCHEMBL9425954 | 0.73 | GABRA1 (0.43) | TSHRALDH1A1LMNAF2 | |
| SCHEMBL3684740 | 0.73 | ATM (0.63) | ACHETDP1MAPTL3MBTL1RXRA | |
| SCHEMBL13110206 | 0.73 | MAPT (0.69) | ACHETDP1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1786807 | 0.73 | MAPT (0.69) | ACHETDP1MAPTL3MBTL1RXRA | |
| SCHEMBL31477014 | 0.72 | ACHE (0.39) | ACHETDP1MAPTL3MBTL1CYP26A1 | |
| SCHEMBL179538 | 0.72 | RXRA (0.66) | ACHETDP1RXRARXRBNR1H4 | |
| SCHEMBL14360801 | 0.72 | TSHR (0.54) | TDP1MAPTL3MBTL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324840-A | Skin disorders | ALLERGAN, INC. (US) | 1994-06-28 | — | — | US | disclosed |