Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152600 | 0.75 | LMNA (0.44) | PTGS2PTGS1AKR1C3LMNAAKR1C2 | |
| SCHEMBL3670597 | 0.75 | LMNA (0.44) | PTGS2PTGS1AKR1C3LMNAAKR1C2 | |
| SCHEMBL7146617 | 0.75 | LMNA (0.44) | PTGS2PTGS1AKR1C3LMNAAKR1C2 | |
| SCHEMBL694753 | 0.74 | PTGS2 (0.65) | PTGS2PTGS1AKR1C3LMNACYP2C9 | |
| SCHEMBL31422536 | 0.73 | AKR1C3 (0.46) | PTGS2PTGS1AKR1C3LMNACYP2C9 | |
| SCHEMBL24875342 | 0.73 | AKR1C3 (0.44) | PTGS2PTGS1AKR1C3LMNACYP2C9 | |
| SCHEMBL3051853 | 0.73 | TSHR (0.50) | PTGS2PTGS1AKR1C3LMNAAKR1C2 | |
| SCHEMBL3180180 | 0.73 | TDP1 (0.40) | PTGS2PTGS1AKR1C3LMNAAKR1C2 | |
| SCHEMBL3169710 | 0.73 | TDP1 (0.40) | PTGS2PTGS1AKR1C3LMNACYP2C9 | |
| SCHEMBL694929 | 0.72 | PTGS2 (0.56) | PTGS2PTGS1AKR1C3LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025085554-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |