SCHEMBL31477474

SCHEMBL31477474

CC(C=O)c1ccc(CCC(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 10/20 0.52
KEAP1 Q14145 1/20 0.50
NPSR1 Q6W5P4 1/20 0.49
ALDH1A1 P00352 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.45
LMNA P02545 1/20 0.45
FFAR4 Q5NUL3 2/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31477497 0.82 CA2 (0.48) FFAR1ALDH1A1LMNACA2RXRA
SCHEMBL879572 0.82 ALDH1A1 (0.59) FFAR1KEAP1NPSR1ALDH1A1L3MBTL1
SCHEMBL27604134 0.80 FFAR1 (0.57) FFAR1KEAP1NPSR1ALDH1A1L3MBTL1
SCHEMBL29010119 0.79 FFAR1 (0.55) FFAR1KEAP1NPSR1ALDH1A1L3MBTL1
SCHEMBL14248263 0.79 FFAR1 (0.55) FFAR1KEAP1NPSR1ALDH1A1L3MBTL1
SCHEMBL29009990 0.79 FFAR1 (0.55) FFAR1KEAP1NPSR1ALDH1A1L3MBTL1
SCHEMBL27649243 0.79 FFAR1 (0.55) FFAR1KEAP1NPSR1ALDH1A1L3MBTL1
SCHEMBL3711064 0.78 ACACB (0.43) ALDH1A1L3MBTL1CA2
SCHEMBL13308116 0.78 ACACB (0.43) ALDH1A1L3MBTL1CA2
SCHEMBL8681618 0.77 ALDH1A1 (0.54) FFAR1KEAP1NPSR1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025085564-A1 LYSINE ACETYLTRANSFERASE INHIBITORS Kronos Bio, Inc. (US) 2025-04-24 WO disclosed
WO-2025085554-A1 LYSINE ACETYLTRANSFERASE INHIBITORS Kronos Bio, Inc. (US) 2025-04-24 WO disclosed