SCHEMBL31477567

SCHEMBL31477567

Fc1cnc2c(c1)NCCC2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.38
NTRK1 P04629 3/20 0.35
ROS1 P08922 1/20 0.32
ADRA2A P08913 2/20 0.32
ADRA2B P18089 2/20 0.32
ADRA2C P18825 2/20 0.32
MAPT P10636 3/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
GAA P10253 1/20 0.31
THRB P10828 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31
HTT P42858 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NNMT P40261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20680569 0.89 GRM5 (0.33)
SCHEMBL15530013 0.78 NNMT (0.34) CYP11B2ADRA2AADRA2BADRA2CMAPT
SCHEMBL20595703 0.78 DYRK1A (0.33) CYP11B2NTRK1ADRA2AADRA2BADRA2C
SCHEMBL13532371 0.78 UHRF1 (0.36) CYP11B2ADRA2AADRA2BADRA2CMAPT
SCHEMBL4980570 0.77 GAA (0.36) CYP11B2MAPTKDM4EALDH1A1GAA
SCHEMBL12942080 0.75 ALDH1A1 (0.36) CYP11B2ADRA2AADRA2BADRA2CMAPT
SCHEMBL1745093 0.74 ADRA2A (0.38) CYP11B2ADRA2AADRA2BADRA2C
SCHEMBL12903038 0.74 HTR1D (0.34) CYP11B2ADRA2AADRA2BADRA2C
SCHEMBL3515984 0.73 NPC1 (0.35) CYP11B2MAPTKDM4ELMNAKMT2A
SCHEMBL5307985 0.73 NPC1 (0.46) NTRK1MAPTKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025085564-A1 LYSINE ACETYLTRANSFERASE INHIBITORS Kronos Bio, Inc. (US) 2025-04-24 WO disclosed