Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148070 | 0.66 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL17108578 | 0.65 | MAPK1 (0.36) | ALDH1A1MAPK1 | |
| SCHEMBL17108577 | 0.65 | MAPK1 (0.36) | ALDH1A1MAPK1MAPT | |
| SCHEMBL28999271 | 0.61 | CYP11B1 (0.38) | ALDH1A1MAPK1ACSS2MAPTKCNN4 | |
| SCHEMBL927921 | 0.60 | PDE5A (0.33) | ALDH1A1MAPK1MAPT | |
| SCHEMBL28789599 | 0.60 | MAPK1 (0.47) | ALDH1A1MAPK1 | |
| SCHEMBL28999325 | 0.60 | CASR (0.33) | MAPK1ACSS2 | |
| SCHEMBL3152762 | 0.59 | TSHR (0.39) | ALDH1A1MAPT | |
| SCHEMBL23399274 | 0.58 | KMT2A (0.42) | ALDH1A1 | |
| SCHEMBL3144333 | 0.58 | POLB (0.35) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099452-B1 | TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING | MALLINCKRODT LLC (US) | 2015-07-22 | — | — | EP | disclosed |
| US-9023315-B2 | Tricarbonyl complexes with tridentate chelators for myocardium imaging | MALLINCKRODT LLC (US) | 2015-05-05 | — | — | US | disclosed |
| US-8940273-B2 | Tricarbonyl complexes with tridentate chelators for myocardium imaging | MALLINCKRODT LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-20130131327-A1 | Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | MALLINCKRODT LLC (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130129620-A1 | Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | MALLINCKRODT LLC (US) | 2013-05-23 | — | — | US | disclosed |
| US-8372379-B2 | Technetium-99m (I) tricarbonyl complexes with tridentate chelators for myocardium imaging | MALLINCKRODT LLC (US) | 2013-02-12 | — | — | US | disclosed |
| US-20100074842-A1 | Technetium-99m (I) Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | LIEBEL-FLARSHEIM COMPANY LLC | 2010-03-25 | — | — | US | disclosed |
| EP-2099452-A2 | TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING | Mallinckrodt Inc. (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008061792-A2 | TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING | MALLINCKRODT INC. (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131327-A1 | Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | TNNT2, TNNI3, FABP3 | ALDH1A1 3518/4885MAPK1 4727/4885ACSS2 490/4885 |
| US-20100074842-A1 | Technetium-99m (I) Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | TNNT2, TNNI3, FABP3 | ALDH1A1 3726/4885MAPK1 4674/4885ACSS2 941/4885 |
| US-20130129620-A1 | Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | TNNT2, TNNI3, FABP3 | ALDH1A1 3518/4885MAPK1 4727/4885ACSS2 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.