Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31478700 | 0.85 | HCRTR1 (0.38) | — | |
| SCHEMBL31479390 | 0.84 | GRM1 (0.43) | — | |
| SCHEMBL31479100 | 0.84 | GPR119 (0.39) | GPR119SMN1; SMN2TRPV3ALOX5APFEN1 | |
| SCHEMBL31479899 | 0.81 | ALOX5AP (0.37) | GPR119SMN1; SMN2ALOX5APFEN1LMNA | |
| SCHEMBL31479892 | 0.80 | GPBAR1 (0.38) | GPR119SMN1; SMN2ALOX5APFEN1 | |
| SCHEMBL31478993 | 0.80 | ENPP2 (0.37) | GPR119SMN1; SMN2LMNATP53MAPT | |
| SCHEMBL31479528 | 0.80 | GPR119 (0.41) | GPR119SMN1; SMN2TP53 | |
| SCHEMBL31479524 | 0.80 | SMN1; SMN2 (0.39) | GPR119SMN1; SMN2TP53 | |
| SCHEMBL31479223 | 0.80 | MAPT (0.37) | GPR119SMN1; SMN2LMNATP53MAPT | |
| SCHEMBL31478741 | 0.79 | MEN1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |