SCHEMBL31479996 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	GPR119	Q8TDV5	8/20	0.37

▸	MAPT	P10636	3/20	0.36

▸	PDK2	Q15119	1/20	0.36

▸	RET	P07949	1/20	0.35

▸	ENPP2	Q13822	1/20	0.35

▸	IDO1	P14902	1/20	0.35

▸	PIK3CA	P42336	1/20	0.35

▸	MEN1	O00255	2/20	0.34

▸	KMT2A	Q03164	2/20	0.34

▸	TSHR	P16473	1/20	0.34

▸	SMN1; SMN2	Q16637	1/20	0.34

▸	WNT3A	P56704	1/20	0.34

▸	LMNA	P02545	2/20	0.34

▸	TP53	P04637	1/20	0.34

▸	THRB	P10828	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31479050	0.88	PREP (0.41)	GPR119MAPTMEN1KMT2A
SCHEMBL31479528	0.87	GPR119 (0.41)	GPR119SMN1; SMN2TP53
SCHEMBL31478993	0.87	ENPP2 (0.37)	GPR119MAPTPDK2RETENPP2
SCHEMBL31478957	0.86	SUV39H2 (0.37)	RETMEN1KMT2A
SCHEMBL31479143	0.86	MAPT (0.40)	GPR119MAPTPDK2RETENPP2
SCHEMBL31479674	0.85	ENPP2 (0.37)	GPR119MAPTPDK2RETENPP2
SCHEMBL31478997	0.85	HCRTR1 (0.36)	MEN1KMT2A
SCHEMBL31479790	0.85	CKS1B (0.37)	GPR119MAPTPDK2RETENPP2
SCHEMBL31479353	0.84	ALOX5AP (0.35)	GPR119MEN1KMT2A
SCHEMBL31479174	0.83	PDE6D (0.37)	MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025067111-A1	MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION	苏州必扬医药科技有限公司	2025-04-03	—	—	WO	disclosed