SCHEMBL31479221 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	TP53	P04637	2/20	0.34

▸	LMNA	P02545	2/20	0.34

▸	MAPT	P10636	1/20	0.34

▸	PLK1	P53350	1/20	0.33

▸	IDO1	P14902	2/20	0.33

▸	TDO2	P48775	1/20	0.33

▸	IDO2	Q6ZQW0	1/20	0.33

▸	GPBAR1	Q8TDU6	1/20	0.32

▸	GPR119	Q8TDV5	1/20	0.31

▸	SQOR	Q9Y6N5	1/20	0.31

▸	THRB	P10828	1/20	0.31

▸	MCHR1	Q99705	1/20	0.31

▸	BACE1	P56817	1/20	0.30

▸	MAPK14	Q16539	1/20	0.30

▸	SMN1; SMN2	Q16637	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31479521	1.00	TP53 (0.34)	TP53LMNAMAPTPLK1IDO1
SCHEMBL31479847	0.95	LMNA (0.34)	TP53LMNAMAPTPLK1IDO1
SCHEMBL31478990	0.95	LMNA (0.34)	TP53LMNAMAPTPLK1IDO1
SCHEMBL31479412	0.93	TP53 (0.35)	TP53LMNAMAPTPLK1IDO1
SCHEMBL31479622	0.91	HTR2A (0.31)	—
SCHEMBL31479489	0.91	HTR2A (0.31)	—
SCHEMBL31479881	0.89	DRD2 (0.31)	—
SCHEMBL31479918	0.89	DRD2 (0.31)	—
SCHEMBL31478941	0.88	GPR119 (0.33)	TP53LMNAMAPTPLK1IDO1
SCHEMBL31478913	0.88	GPBAR1 (0.39)	GPBAR1GPR119BACE1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025067111-A1	MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION	苏州必扬医药科技有限公司	2025-04-03	—	—	WO	disclosed