Sugi Predict

Sugi Predict / Compounds / SCHEMBL31479243

SCHEMBL31479243

SCHEMBL31479243

Cc1cn2c(C3CCN(C(=O)OC(C)(C)C)CC3)cc(-c3ccc(F)cc3C(=O)N(CC(F)F)C(C)C)c2cn1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 3/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ LMNA P02545 3/20 0.37
▸ TP53 P04637 3/20 0.37
▸ MAPT P10636 1/20 0.37
▸ THRB P10828 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ USP30 Q70CQ3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31479901 0.89 GPR119 (0.40) GPR119SMN1; SMN2LMNATP53POLB
SCHEMBL31479524 0.88 SMN1; SMN2 (0.39) GPR119SMN1; SMN2TP53POLB
SCHEMBL31479532 0.86 SLC6A2 (0.35) TP53THRB
SCHEMBL31479587 0.85 GPR119 (0.39) GPR119SMN1; SMN2TP53POLBUSP30
SCHEMBL31479192 0.85 GPR119 (0.39) GPR119SMN1; SMN2TP53POLBUSP30
SCHEMBL31478913 0.82 GPBAR1 (0.39) GPR119SMN1; SMN2POLBUSP30
SCHEMBL31479700 0.82 RET (0.37) GPR119SMN1; SMN2MAPT
SCHEMBL31479651 0.81 GPBAR1 (0.41) GPR119SMN1; SMN2
SCHEMBL31479270 0.80 MEN1 (0.47) —
SCHEMBL31479100 0.79 GPR119 (0.39) GPR119SMN1; SMN2TP53POLBUSP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067111-A1 MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION 苏州必扬医药科技有限公司 2025-04-03 — — WO disclosed