Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479651 | 0.93 | GPBAR1 (0.41) | GPR119SMN1; SMN2GPBAR1 | |
| SCHEMBL31479243 | 0.89 | GPR119 (0.40) | GPR119SMN1; SMN2LMNAPOLBTP53 | |
| SCHEMBL31479473 | 0.86 | PLAT (0.33) | TP53GPBAR1 | |
| SCHEMBL31479547 | 0.84 | GPBAR1 (0.33) | GPBAR1 | |
| SCHEMBL31479524 | 0.82 | SMN1; SMN2 (0.39) | GPR119SMN1; SMN2POLBTP53 | |
| SCHEMBL31479095 | 0.81 | GPBAR1 (0.32) | GPBAR1 | |
| SCHEMBL31478951 | 0.80 | MEN1 (0.47) | — | |
| SCHEMBL31479192 | 0.80 | GPR119 (0.39) | GPR119SMN1; SMN2POLBTP53GPBAR1 | |
| SCHEMBL31479587 | 0.80 | GPR119 (0.39) | GPR119SMN1; SMN2POLBTP53GPBAR1 | |
| SCHEMBL31479528 | 0.77 | GPR119 (0.41) | GPR119SMN1; SMN2POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |