Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631265 | 0.79 | KDM4E (0.33) | KDM4ENPC1MAPK1RAB9ACHEK1 | |
| SCHEMBL25516750 | 0.70 | CYP2A6 (0.32) | KDM4ECHEK1ALDH1A1MAPTLIMK1 | |
| Hydrochloric Acid SCHEMBL6229671 | 0.69 | KDM4E (0.44) | KDM4EMAPK1ALDH1A1MAPTTDP1 | |
| SCHEMBL20116291 | 0.68 | CYP1A2 (0.38) | KDM4ENPC1MAPK1RAB9ACHEK1 | |
| SCHEMBL26690104 | 0.67 | SMN1; SMN2 (0.37) | KDM4ENPC1MAPK1RAB9AALDH1A1 | |
| SCHEMBL23293949 | 0.65 | L3MBTL1 (0.43) | KDM4EGAA | |
| SCHEMBL31748007 | 0.65 | LMNA (0.33) | — | |
| SCHEMBL31748001 | 0.65 | HTT (0.31) | — | |
| SCHEMBL25172368 | 0.64 | UHRF1 (0.33) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL31569340 | 0.63 | SCN5A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |